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MALT lymphoma: epidemiology, clinical diagnosis and treatment
Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197515/ https://www.ncbi.nlm.nih.gov/pubmed/30364585 http://dx.doi.org/10.25122/jml-2018-0035 |
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author | Violeta Filip, Petruta Cuciureanu, Denisa Sorina Diaconu, Laura Maria Vladareanu, Ana Silvia Pop, Corina |
author_facet | Violeta Filip, Petruta Cuciureanu, Denisa Sorina Diaconu, Laura Maria Vladareanu, Ana Silvia Pop, Corina |
author_sort | Violeta Filip, Petruta |
collection | PubMed |
description | Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-cell lymphoma (DLBCL). During the years, clinical trials revealed the important role of Helicobacter pylori (H. pylori) in the pathogenesis of gastric MALT lymphoma. Infection with Helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. Long-term studies revealed that eradication therapy could regress gastric lymphomas. |
format | Online Article Text |
id | pubmed-6197515 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61975152018-10-25 MALT lymphoma: epidemiology, clinical diagnosis and treatment Violeta Filip, Petruta Cuciureanu, Denisa Sorina Diaconu, Laura Maria Vladareanu, Ana Silvia Pop, Corina J Med Life Review Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-cell lymphoma (DLBCL). During the years, clinical trials revealed the important role of Helicobacter pylori (H. pylori) in the pathogenesis of gastric MALT lymphoma. Infection with Helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. Long-term studies revealed that eradication therapy could regress gastric lymphomas. Carol Davila University Press 2018 /pmc/articles/PMC6197515/ /pubmed/30364585 http://dx.doi.org/10.25122/jml-2018-0035 Text en ©Carol Davila University Press This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Review Violeta Filip, Petruta Cuciureanu, Denisa Sorina Diaconu, Laura Maria Vladareanu, Ana Silvia Pop, Corina MALT lymphoma: epidemiology, clinical diagnosis and treatment |
title | MALT lymphoma: epidemiology, clinical diagnosis and treatment |
title_full | MALT lymphoma: epidemiology, clinical diagnosis and treatment |
title_fullStr | MALT lymphoma: epidemiology, clinical diagnosis and treatment |
title_full_unstemmed | MALT lymphoma: epidemiology, clinical diagnosis and treatment |
title_short | MALT lymphoma: epidemiology, clinical diagnosis and treatment |
title_sort | malt lymphoma: epidemiology, clinical diagnosis and treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197515/ https://www.ncbi.nlm.nih.gov/pubmed/30364585 http://dx.doi.org/10.25122/jml-2018-0035 |
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