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LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation

BACKGROUND: MicroRNA-122 (miR-122), a pivotal liver-specific miRNA, is frequently repressed in hepatocellular carcinoma (HCC) and associated with poor prognosis. Long non-coding RNA (lncRNA) HOTAIR has been proved to function as an oncogene in multiple cancers including HCC. However, the relationshi...

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Detalles Bibliográficos
Autores principales:	Cheng, Di, Deng, Junge, Zhang, Bin, He, Xiaoyu, Meng, Zhe, Li, Guolin, Ye, Huilin, Zheng, Shangyou, Wei, Lusheng, Deng, Xiaogeng, Chen, Rufu, Zhou, Jiajia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197532/ https://www.ncbi.nlm.nih.gov/pubmed/30195653 http://dx.doi.org/10.1016/j.ebiom.2018.08.055

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