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l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism

OBJECTIVE: AMP activated protein kinase (AMPK) is recognized as an important nutrient sensor contributing to regulation of cellular, tissue, and systemic metabolism. We aimed to identify specific amino acids which could modulate AMPK and determine effects on cellular and systemic metabolism. METHODS...

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Detalles Bibliográficos
Autores principales:	Adachi, Yusuke, De Sousa-Coelho, Ana Luisa, Harata, Ikue, Aoun, Charlie, Weimer, Sandra, Shi, Xu, Gonzalez Herrera, Karina N., Takahashi, Hirokazu, Doherty, Chris, Noguchi, Yasushi, Goodyear, Laurie J., Haigis, Marcia C., Gerszten, Robert E., Patti, Mary-Elizabeth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197624/ https://www.ncbi.nlm.nih.gov/pubmed/30190193 http://dx.doi.org/10.1016/j.molmet.2018.08.002

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