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Aerosol prime-boost vaccination provides strong protection in outbred rabbits against virulent type A Francisella tularensis
Tularemia, also known as rabbit fever, is a severe zoonotic disease in humans caused by the gram-negative bacterium Francisella tularensis (Ft). While there have been a number of attempts to develop a vaccine for Ft, few candidates have advanced beyond experiments in inbred mice. We report here that...
Autores principales: | O’Malley, Katherine J., Bowling, Jennifer L., Stinson, Elizabeth, Cole, Kelly S., Mann, Barbara J., Namjoshi, Prachi, Hazlett, Karsten R. O., Barry, Eileen M., Reed, Douglas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197691/ https://www.ncbi.nlm.nih.gov/pubmed/30346998 http://dx.doi.org/10.1371/journal.pone.0205928 |
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