IFN-γ immune priming of macrophages in vivo induces prolonged STAT1 binding and protection against Cryptococcus neoformans

Development of vaccines against opportunistic infections is difficult as patients most at risk of developing disease are deficient in aspects of the adaptive immune system. Here, we utilized an experimental immunization strategy to induce innate memory in macrophages in vivo. Unlike current trained...

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Detalles Bibliográficos
Autores principales: Leopold Wager, Chrissy M., Hole, Camaron R., Campuzano, Althea, Castro-Lopez, Natalia, Cai, Hong, Caballero Van Dyke, Marley C., Wozniak, Karen L., Wang, Yufeng, Wormley, Floyd L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197699/
https://www.ncbi.nlm.nih.gov/pubmed/30304063
http://dx.doi.org/10.1371/journal.ppat.1007358

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