Cells isolated from residual intracranial tumors after treatment express iPSC genes and possess neural lineage differentiation plasticity

BACKGROUND: The goal of this study is to identify and characterize treatment resistant tumor initiating cells (TRTICs) using orthotopic xenografts. METHODS: TRTICs were enriched from GBM cell lines using mouse xenografts treated with fractionated doses of radiation and temozolomide. TRTICs were char...

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Detalles Bibliográficos
Autores principales: Palanichamy, Kamalakannan, Jacob, John R., Litzenberg, Kevin T., Ray-Chaudhury, Abhik, Chakravarti, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197705/
https://www.ncbi.nlm.nih.gov/pubmed/30269995
http://dx.doi.org/10.1016/j.ebiom.2018.09.019

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