Impacts of Diabetes and an SGLT2 Inhibitor on the Glomerular Number and Volume in db/db Mice, as Estimated by Synchrotron Radiation Micro-CT at SPring-8

BACKGROUND: Recent large-scale clinical studies demonstrate that sodium-glucose cotransporter 2 (SGLT2) inhibitors protect the diabetic kidney. However, clinical and animal studies have not shown the changes of the total glomeruli in the whole kidney treated with SGLT2 inhibitors. METHODS: We perfor...

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Detalles Bibliográficos
Autores principales: Takiyama, Yumi, Sera, Toshihiro, Nakamura, Masanori, Ishizeki, Kanaki, Saijo, Yasuaki, Yanagimachi, Tsuyoshi, Maeda, Manami, Bessho, Ryoichi, Takiyama, Takao, Kitsunai, Hiroya, Sakagami, Hidemitsu, Fujishiro, Daisuke, Fujita, Yukihiro, Makino, Yuichi, Abiko, Atsuko, Hoshino, Masato, Uesugi, Kentaro, Yagi, Naoto, Ota, Tsuguhito, Haneda, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197731/
https://www.ncbi.nlm.nih.gov/pubmed/30322799
http://dx.doi.org/10.1016/j.ebiom.2018.09.048

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