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PI3Kγ promotes vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis via a SOX9-dependent mechanism

BACKGROUND: Transplant arteriosclerosis (TA) remains the major cause of chronic graft failure in solid organ transplantation. The phenotypic modulation of vascular smooth muscle cells (VSMCs) is a key event for the initiation and progression of neointimal formation and TA. This study aims to explore...

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Detalles Bibliográficos
Autores principales: Yu, Qihong, Li, Wei, Xie, Dawei, Zheng, Xichuan, Huang, Tong, Xue, Ping, Guo, Bing, Gao, Yang, Zhang, Chen, Sun, Ping, Li, Min, Wang, Guoliang, Cheng, Xiang, Zheng, Qichang, Song, Zifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197754/
https://www.ncbi.nlm.nih.gov/pubmed/30241919
http://dx.doi.org/10.1016/j.ebiom.2018.09.013

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