Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules

The ability of transcriptional regulators to drive lineage conversion of somatic cells offers great potential for the treatment of human disease. To explore the concept of switching on specific target genes in heterologous cells, we developed a model system to screen candidate factors for their abil...

Descripción completa

Detalles Bibliográficos
Autores principales: Artuz, Crisbel M., Knights, Alexander J., Funnell, Alister P.W., Gonda, Thomas J., Ravid, Katya, Pearson, Richard C.M., Quinlan, Kate G.R., Crossley, Merlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197760/
https://www.ncbi.nlm.nih.gov/pubmed/30364711
http://dx.doi.org/10.1016/j.btre.2018.e00285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197760/
https://www.ncbi.nlm.nih.gov/pubmed/30364711
http://dx.doi.org/10.1016/j.btre.2018.e00285

Ejemplares similares