T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways

OBJECTIVE: Beyond the taste buds, sweet taste receptors (STRs; T1R2/T1R3) are also expressed on enteroendocrine cells, where they regulate gut peptide secretion but their regulatory function within the intestine is largely unknown. METHODS: Using T1R2-knock out (KO) mice we evaluated the role of STR...

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Detalles Bibliográficos
Autores principales: Smith, Kathleen, Karimian Azari, Elnaz, LaMoia, Traci E., Hussain, Tania, Vargova, Veronika, Karolyi, Katalin, Veldhuis, Paula P., Arnoletti, Juan Pablo, de la Fuente, Sebastian G., Pratley, Richard E., Osborne, Timothy F., Kyriazis, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197762/
https://www.ncbi.nlm.nih.gov/pubmed/30201274
http://dx.doi.org/10.1016/j.molmet.2018.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197762/
https://www.ncbi.nlm.nih.gov/pubmed/30201274
http://dx.doi.org/10.1016/j.molmet.2018.08.009

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