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mTORC1 Overactivation as a Key Aging Factor in the Progression to Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM), a worldwide epidemics, is a progressive disease initially developing an insulin resistant state, with manifest pancreatic beta islet overwork and hyperinsulinemia. As the disease progresses, pancreatic β cells are overwhelmed and fails in their capacity to compensate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198057/ https://www.ncbi.nlm.nih.gov/pubmed/30386301 http://dx.doi.org/10.3389/fendo.2018.00621 |