Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids

BACKGROUND & AIMS: Microvillus inclusion disease (MVID) is a congenital intestinal malabsorption disorder caused by defective apical vesicular transport. Existing cellular models do not fully recapitulate this heterogeneous pathology. The aim of this study was to characterize 3-dimensional intes...

Descripción completa

Detalles Bibliográficos
Autores principales: Mosa, Mohammed H., Nicolle, Ophélie, Maschalidi, Sophia, Sepulveda, Fernando E., Bidaud-Meynard, Aurelien, Menche, Constantin, Michels, Birgitta E., Michaux, Grégoire, de Saint Basile, Geneviève, Farin, Henner F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198061/
https://www.ncbi.nlm.nih.gov/pubmed/30364784
http://dx.doi.org/10.1016/j.jcmgh.2018.08.001

Ejemplares similares

Ejemplares similares