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Phosphorothioate-Modified AP613-1 Specifically Targets GPC3 when Used for Hepatocellular Carcinoma Cell Imaging

Glypican-3 (GPC3), the cellular membrane proteoglycan, has been established as a tumor biomarker for early diagnosis of hepatocellular carcinoma (HCC). GPC3 is highly expressed in more than 70% HCC tissues detected by antibody-based histopathological systems. Recently, aptamers, a short single-stran...

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Detalles Bibliográficos
Autores principales:	Dong, Lili, Zhou, Hongxin, Zhao, Menglong, Gao, Xinghui, Liu, Yang, Liu, Dongli, Guo, Wei, Hu, Hongwei, Xie, Qian, Fan, Jia, Lin, Jiang, Wu, Weizhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198100/ https://www.ncbi.nlm.nih.gov/pubmed/30347351 http://dx.doi.org/10.1016/j.omtn.2018.09.013

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