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Chronic Psychosocial Stress in Mice Is Associated With Increased Acid Sphingomyelinase Activity in Liver and Serum and With Hepatic C16:0-Ceramide Accumulation

Chronic psychosocial stress adversely affects human morbidity and is a risk factor for inflammatory disorders, liver diseases, obesity, metabolic syndrome, and major depressive disorder (MDD). In recent studies, we found an association of MDD with an increase of acid sphingomyelinase (ASM) activity....

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Detalles Bibliográficos
Autores principales: Reichel, Martin, Rhein, Cosima, Hofmann, Lena M., Monti, Juliana, Japtok, Lukasz, Langgartner, Dominik, Füchsl, Andrea M., Kleuser, Burkhard, Gulbins, Erich, Hellerbrand, Claus, Reber, Stefan O., Kornhuber, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198178/
https://www.ncbi.nlm.nih.gov/pubmed/30386262
http://dx.doi.org/10.3389/fpsyt.2018.00496