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CSF1R Inhibition Reduces Microglia Proliferation, Promotes Tissue Preservation and Improves Motor Recovery After Spinal Cord Injury
Spinal cord injury (SCI) induces a pronounced neuroinflammation driven by activation and proliferation of resident microglia as well as infiltrating peripheral monocyte-derived macrophages. Depending on the time post-lesion, positive and detrimental influences of microglia/macrophages on axonal rege...
Autores principales: | Gerber, Yannick Nicolas, Saint-Martin, Guillaume Patrick, Bringuier, Claire Mathilde, Bartolami, Sylvain, Goze-Bac, Christophe, Noristani, Harun Najib, Perrin, Florence Evelyne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198221/ https://www.ncbi.nlm.nih.gov/pubmed/30386212 http://dx.doi.org/10.3389/fncel.2018.00368 |
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