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Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress
Compelling evidence has shown that, besides its putative effect on the regulation of the gonadal axis, estradiol (E2) exerts a dichotomic effect on the hypothalamus to regulate food intake and energy expenditure. The anorectic effect of E2 is mainly mediated by its action on the arcuate nucleus (ARC...
Autores principales: | González-García, Ismael, Contreras, Cristina, Estévez-Salguero, Ánxela, Ruíz-Pino, Francisco, Colsh, Benoit, Pensado, Iván, Liñares-Pose, Laura, Rial-Pensado, Eva, Martínez de Morentin, Pablo B., Fernø, Johan, Diéguez, Carlos, Nogueiras, Rubén, Le Stunff, Hervé, Magnan, Christophe, Tena-Sempere, Manuel, López, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198289/ https://www.ncbi.nlm.nih.gov/pubmed/30304681 http://dx.doi.org/10.1016/j.celrep.2018.09.038 |
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