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A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China
Patients with swimming pool-acquired human adenovirus (HAdV) infections usually manifest characteristic clinical features that include fever, pharyngitis, and conjunctival inflammation, syndromically referred to as pharyngoconjunctival fever (PCF). HAdV types 3, 4, and 7 are most commonly associated...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198331/ https://www.ncbi.nlm.nih.gov/pubmed/30144556 http://dx.doi.org/10.1016/j.ijid.2018.08.009 |
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author | Li, Jie Lu, Xiaoyan Sun, Yamin Lin, Changying Li, Feng Yang, Yang Liang, Zhichao Jia, Lei Chen, Lijuan Jiang, Baoming Wang, Quanyi |
author_facet | Li, Jie Lu, Xiaoyan Sun, Yamin Lin, Changying Li, Feng Yang, Yang Liang, Zhichao Jia, Lei Chen, Lijuan Jiang, Baoming Wang, Quanyi |
author_sort | Li, Jie |
collection | PubMed |
description | Patients with swimming pool-acquired human adenovirus (HAdV) infections usually manifest characteristic clinical features that include fever, pharyngitis, and conjunctival inflammation, syndromically referred to as pharyngoconjunctival fever (PCF). HAdV types 3, 4, and 7 are most commonly associated with PCF. This article reports an outbreak of PCF that involved 55 students and staff at a university in Beijing, China. Fifty patients had used the same swimming pool 2 weeks before the onset of symptoms. HAdV type 4 was identified from patient eye and throat swabs and concentrated swimming pool water samples. Partial hexon gene sequences obtained from the water samples were 100% identical to the sequences obtained from the swab samples, which clustered with HAdV-4 within species E. Swimming pool water contaminated with HAdV-4 was the most likely source of infection, although one instance of likely person-to-person transmission was noted. |
format | Online Article Text |
id | pubmed-6198331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
record_format | MEDLINE/PubMed |
spelling | pubmed-61983312018-10-23 A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China Li, Jie Lu, Xiaoyan Sun, Yamin Lin, Changying Li, Feng Yang, Yang Liang, Zhichao Jia, Lei Chen, Lijuan Jiang, Baoming Wang, Quanyi Int J Infect Dis Article Patients with swimming pool-acquired human adenovirus (HAdV) infections usually manifest characteristic clinical features that include fever, pharyngitis, and conjunctival inflammation, syndromically referred to as pharyngoconjunctival fever (PCF). HAdV types 3, 4, and 7 are most commonly associated with PCF. This article reports an outbreak of PCF that involved 55 students and staff at a university in Beijing, China. Fifty patients had used the same swimming pool 2 weeks before the onset of symptoms. HAdV type 4 was identified from patient eye and throat swabs and concentrated swimming pool water samples. Partial hexon gene sequences obtained from the water samples were 100% identical to the sequences obtained from the swab samples, which clustered with HAdV-4 within species E. Swimming pool water contaminated with HAdV-4 was the most likely source of infection, although one instance of likely person-to-person transmission was noted. 2018-08-23 2018-10 /pmc/articles/PMC6198331/ /pubmed/30144556 http://dx.doi.org/10.1016/j.ijid.2018.08.009 Text en This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Li, Jie Lu, Xiaoyan Sun, Yamin Lin, Changying Li, Feng Yang, Yang Liang, Zhichao Jia, Lei Chen, Lijuan Jiang, Baoming Wang, Quanyi A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China |
title | A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China |
title_full | A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China |
title_fullStr | A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China |
title_full_unstemmed | A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China |
title_short | A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China |
title_sort | swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in beijing, china |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198331/ https://www.ncbi.nlm.nih.gov/pubmed/30144556 http://dx.doi.org/10.1016/j.ijid.2018.08.009 |
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