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High-fat, high-sugar diet induces splenomegaly that is ameliorated with exercise and genistein treatment
OBJECTIVE: We tested the effect of exercise training and genistein treatment on splenomegaly in mice fed a high-fat, high-sugar diet (HFSD). RESULTS: Male and female C57BL6 mice fed HFSD containing 60% fat along with drinking water containing 42 g/L sugar (55% sucrose/45% fructose) for 12 weeks exhi...
Autores principales: | Buchan, Levi, St. Aubin, Chaheyla R., Fisher, Amy L., Hellings, Austin, Castro, Monica, Al-Nakkash, Layla, Broderick, Tom L., Plochocki, Jeffrey H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198361/ https://www.ncbi.nlm.nih.gov/pubmed/30348225 http://dx.doi.org/10.1186/s13104-018-3862-z |
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