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Identification of SUV39H2 as a potential oncogene in lung adenocarcinoma

BACKGROUND: SUV39H2 (suppressor of variegation 3-9 homolog 2), which introduces H3K9me3 to induce transcriptional repression, has been reported to play critical roles in heterochromatin maintenance, DNA repair, and recently, carcinogenesis. Dysregulation of SUV39H2 expression has been observed in se...

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Detalles Bibliográficos
Autores principales: Zheng, Yu, Li, Baihui, Wang, Jian, Xiong, Yanjuan, Wang, Kaiyuan, Qi, Ying, Sun, Houfang, Wu, Lei, Yang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198372/
https://www.ncbi.nlm.nih.gov/pubmed/30348215
http://dx.doi.org/10.1186/s13148-018-0562-4

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