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Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

BACKGROUND: Bone is one of the most frequent metastatic sites of advanced breast cancer. Current therapeutic agents aim to inhibit osteoclast-mediated bone resorption but only have palliative effects. During normal bone remodeling, the balance between bone resorption and osteoblast-mediated bone for...

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Detalles Bibliográficos
Autores principales:	Liu, Xuxiang, Cao, Minghui, Palomares, Melanie, Wu, Xiwei, Li, Arthur, Yan, Wei, Fong, Miranda Y., Chan, Wing-Chung, Wang, Shizhen Emily
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198446/ https://www.ncbi.nlm.nih.gov/pubmed/30348200 http://dx.doi.org/10.1186/s13058-018-1059-y

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