Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica

BACKGROUND: Aquaporin-4-immunoglobulin G (AQP4-IgG) seropositive neuromyelitis optica spectrum disorder (herein called NMO) is an autoimmune disease of the central nervous system in which AQP4-IgG binding to AQP4 on astrocytes results in complement-dependent astrocyte injury and secondary inflammati...

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Detalles Bibliográficos
Autores principales: Duan, Tianjiao, Smith, Alex J., Verkman, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198534/
https://www.ncbi.nlm.nih.gov/pubmed/30348195
http://dx.doi.org/10.1186/s12974-018-1333-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198534/
https://www.ncbi.nlm.nih.gov/pubmed/30348195
http://dx.doi.org/10.1186/s12974-018-1333-z

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