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Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark

Polypharmacy is common among multimorbid adults and associated with increased morbidity and mortality. Excessive polypharmacy (ie, ≥10 medicine) is strongly associated with inappropriate medication use, but little is known about attitudes toward deprescribing in patients with excessive polypharmacy....

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Autores principales: Schiøtz, Michaela L., Frølich, Anne, Jensen, Anette K., Reuther, Lene, Perrild, Hans, Petersen, Tonny S., Kornholt, Jonatan, Christensen, Mikkel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198567/
https://www.ncbi.nlm.nih.gov/pubmed/30386624
http://dx.doi.org/10.1002/prp2.431
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author Schiøtz, Michaela L.
Frølich, Anne
Jensen, Anette K.
Reuther, Lene
Perrild, Hans
Petersen, Tonny S.
Kornholt, Jonatan
Christensen, Mikkel B.
author_facet Schiøtz, Michaela L.
Frølich, Anne
Jensen, Anette K.
Reuther, Lene
Perrild, Hans
Petersen, Tonny S.
Kornholt, Jonatan
Christensen, Mikkel B.
author_sort Schiøtz, Michaela L.
collection PubMed
description Polypharmacy is common among multimorbid adults and associated with increased morbidity and mortality. Excessive polypharmacy (ie, ≥10 medicine) is strongly associated with inappropriate medication use, but little is known about attitudes toward deprescribing in patients with excessive polypharmacy. We surveyed 100 Danish individuals aged 65 years and above with ≥10 prescribed medications, using the validated Patients’ Attitudes Towards Deprescribing (PATD) instrument. Most participants (81, 81%) thought they took a large number of medications, and 79 (79%) believed that their medications were necessary. Even so, 85 (85%) reported that they would be willing to stop taking one or more of their regular medications if their doctor told them they could, and 11 (11%) felt that they took at least one regular medication that they no longer needed. When presented with visual presentation of various amounts of tablets and capsules, 62 (62%) of participants reported that they would be comfortable taking fewer medications than they did. Forty‐two (42%) participants had experience with stopping a regular medication. Almost all participants (92%) wanted to receive follow‐up by various means if a medication was discontinued. Forty‐one (41%) participants were interested in a consultation at an outpatient clinic specializing in polypharmacy. Overall, the answers to the PATD questionnaire suggest that our cohort of Danish, multimorbid outpatients with extensive polypharmacy have a high confidence in their healthcare providers for medication‐related decisions, even though some feel that they are taking more medications than they would like to and feel that some medications may be unnecessary. Our results underline the need for healthcare providers to offer medication reviews in patients with multimorbidity.
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spelling pubmed-61985672018-10-31 Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark Schiøtz, Michaela L. Frølich, Anne Jensen, Anette K. Reuther, Lene Perrild, Hans Petersen, Tonny S. Kornholt, Jonatan Christensen, Mikkel B. Pharmacol Res Perspect Original Articles Polypharmacy is common among multimorbid adults and associated with increased morbidity and mortality. Excessive polypharmacy (ie, ≥10 medicine) is strongly associated with inappropriate medication use, but little is known about attitudes toward deprescribing in patients with excessive polypharmacy. We surveyed 100 Danish individuals aged 65 years and above with ≥10 prescribed medications, using the validated Patients’ Attitudes Towards Deprescribing (PATD) instrument. Most participants (81, 81%) thought they took a large number of medications, and 79 (79%) believed that their medications were necessary. Even so, 85 (85%) reported that they would be willing to stop taking one or more of their regular medications if their doctor told them they could, and 11 (11%) felt that they took at least one regular medication that they no longer needed. When presented with visual presentation of various amounts of tablets and capsules, 62 (62%) of participants reported that they would be comfortable taking fewer medications than they did. Forty‐two (42%) participants had experience with stopping a regular medication. Almost all participants (92%) wanted to receive follow‐up by various means if a medication was discontinued. Forty‐one (41%) participants were interested in a consultation at an outpatient clinic specializing in polypharmacy. Overall, the answers to the PATD questionnaire suggest that our cohort of Danish, multimorbid outpatients with extensive polypharmacy have a high confidence in their healthcare providers for medication‐related decisions, even though some feel that they are taking more medications than they would like to and feel that some medications may be unnecessary. Our results underline the need for healthcare providers to offer medication reviews in patients with multimorbidity. John Wiley and Sons Inc. 2018-10-23 /pmc/articles/PMC6198567/ /pubmed/30386624 http://dx.doi.org/10.1002/prp2.431 Text en © 2018 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Schiøtz, Michaela L.
Frølich, Anne
Jensen, Anette K.
Reuther, Lene
Perrild, Hans
Petersen, Tonny S.
Kornholt, Jonatan
Christensen, Mikkel B.
Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark
title Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark
title_full Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark
title_fullStr Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark
title_full_unstemmed Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark
title_short Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark
title_sort polypharmacy and medication deprescribing: a survey among multimorbid older adults in denmark
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198567/
https://www.ncbi.nlm.nih.gov/pubmed/30386624
http://dx.doi.org/10.1002/prp2.431
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