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Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management
Acute respiratory distress syndrome (ARDS) is characterized by severe inflammatory response and hypoxemia. The use of mechanical ventilation (MV) for correction of gas exchange can cause worsening of this inflammatory response, called “ventilator-induced lung injury” (VILI). The process of withdrawi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198583/ https://www.ncbi.nlm.nih.gov/pubmed/30402484 http://dx.doi.org/10.1155/2018/5423639 |
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author | Wawrzeniak, Iuri Christmann Regina Rios Vieira, Silvia Almeida Victorino, Josué |
author_facet | Wawrzeniak, Iuri Christmann Regina Rios Vieira, Silvia Almeida Victorino, Josué |
author_sort | Wawrzeniak, Iuri Christmann |
collection | PubMed |
description | Acute respiratory distress syndrome (ARDS) is characterized by severe inflammatory response and hypoxemia. The use of mechanical ventilation (MV) for correction of gas exchange can cause worsening of this inflammatory response, called “ventilator-induced lung injury” (VILI). The process of withdrawing mechanical ventilation, referred to as weaning from MV, may cause worsening of lung injury by spontaneous ventilation. Currently, there are few specific studies in patients with ARDS. Herein, we reviewed the main aspects of spontaneous ventilation and also discussed potential methods to predict the failure of weaning in this patient category. We also reviewed new treatments (modes of mechanical ventilation, neuromuscular blocker use, and extracorporeal membrane oxygenation) that could be considered in weaning ARDS patients from MV. |
format | Online Article Text |
id | pubmed-6198583 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-61985832018-11-06 Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management Wawrzeniak, Iuri Christmann Regina Rios Vieira, Silvia Almeida Victorino, Josué Biomed Res Int Review Article Acute respiratory distress syndrome (ARDS) is characterized by severe inflammatory response and hypoxemia. The use of mechanical ventilation (MV) for correction of gas exchange can cause worsening of this inflammatory response, called “ventilator-induced lung injury” (VILI). The process of withdrawing mechanical ventilation, referred to as weaning from MV, may cause worsening of lung injury by spontaneous ventilation. Currently, there are few specific studies in patients with ARDS. Herein, we reviewed the main aspects of spontaneous ventilation and also discussed potential methods to predict the failure of weaning in this patient category. We also reviewed new treatments (modes of mechanical ventilation, neuromuscular blocker use, and extracorporeal membrane oxygenation) that could be considered in weaning ARDS patients from MV. Hindawi 2018-10-09 /pmc/articles/PMC6198583/ /pubmed/30402484 http://dx.doi.org/10.1155/2018/5423639 Text en Copyright © 2018 Iuri Christmann Wawrzeniak et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Wawrzeniak, Iuri Christmann Regina Rios Vieira, Silvia Almeida Victorino, Josué Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management |
title | Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management |
title_full | Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management |
title_fullStr | Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management |
title_full_unstemmed | Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management |
title_short | Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management |
title_sort | weaning from mechanical ventilation in ards: aspects to think about for better understanding, evaluation, and management |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198583/ https://www.ncbi.nlm.nih.gov/pubmed/30402484 http://dx.doi.org/10.1155/2018/5423639 |
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