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To identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events

BACKGROUND AND OBJECTIVES: Relapse is a complex and dynamic phenomenon that appears to be determined by biological, psychological, and social factors and an interaction among these. This study examined the association between demographic variables, clinical parameters, and psychosocial factors that...

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Autores principales: Chauhan, Vinay Singh, Nautiyal, Shubra, Garg, Rajat, Chauhan, Kirti S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198591/
https://www.ncbi.nlm.nih.gov/pubmed/30416295
http://dx.doi.org/10.4103/ipj.ipj_27_18
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author Chauhan, Vinay Singh
Nautiyal, Shubra
Garg, Rajat
Chauhan, Kirti S
author_facet Chauhan, Vinay Singh
Nautiyal, Shubra
Garg, Rajat
Chauhan, Kirti S
author_sort Chauhan, Vinay Singh
collection PubMed
description BACKGROUND AND OBJECTIVES: Relapse is a complex and dynamic phenomenon that appears to be determined by biological, psychological, and social factors and an interaction among these. This study examined the association between demographic variables, clinical parameters, and psychosocial factors that predict the vulnerability to relapse in cases of alcohol dependence syndrome. MATERIALS AND METHODS: Structured assessments of clinical/demographic parameters, relapse precipitants, life events, and dysfunction were carried out among patients with alcohol dependence syndrome (n = 100) who had relapsed and compared with those (n = 100) who had managed to remain abstinent. RESULTS: Patients who had relapsed were found to have significantly more positive family history of substance use, past history of alcohol-related comorbidity, experienced a higher number of undesirable life events, and higher negative mood states and social anxiety and dysfunction in social, vocational, personal, family, and cognitive spheres compared to patients who had remained abstinent. CONCLUSIONS: Relapse in alcohol dependents is an interaction of many factors, and multiple layers of assessment may be required to predict relapse. This study provided further evidence in support of the importance of certain clinical/psychosocial factors in relapse in substance dependence. It provides the basis for investigating the correlates of relapse in a wide range of behavioral and substance use problems.
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spelling pubmed-61985912018-11-09 To identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events Chauhan, Vinay Singh Nautiyal, Shubra Garg, Rajat Chauhan, Kirti S Ind Psychiatry J Original Article BACKGROUND AND OBJECTIVES: Relapse is a complex and dynamic phenomenon that appears to be determined by biological, psychological, and social factors and an interaction among these. This study examined the association between demographic variables, clinical parameters, and psychosocial factors that predict the vulnerability to relapse in cases of alcohol dependence syndrome. MATERIALS AND METHODS: Structured assessments of clinical/demographic parameters, relapse precipitants, life events, and dysfunction were carried out among patients with alcohol dependence syndrome (n = 100) who had relapsed and compared with those (n = 100) who had managed to remain abstinent. RESULTS: Patients who had relapsed were found to have significantly more positive family history of substance use, past history of alcohol-related comorbidity, experienced a higher number of undesirable life events, and higher negative mood states and social anxiety and dysfunction in social, vocational, personal, family, and cognitive spheres compared to patients who had remained abstinent. CONCLUSIONS: Relapse in alcohol dependents is an interaction of many factors, and multiple layers of assessment may be required to predict relapse. This study provided further evidence in support of the importance of certain clinical/psychosocial factors in relapse in substance dependence. It provides the basis for investigating the correlates of relapse in a wide range of behavioral and substance use problems. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6198591/ /pubmed/30416295 http://dx.doi.org/10.4103/ipj.ipj_27_18 Text en Copyright: © 2018 Industrial Psychiatry Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Chauhan, Vinay Singh
Nautiyal, Shubra
Garg, Rajat
Chauhan, Kirti S
To identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events
title To identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events
title_full To identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events
title_fullStr To identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events
title_full_unstemmed To identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events
title_short To identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events
title_sort to identify predictors of relapse in cases of alcohol dependence syndrome in relation to life events
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198591/
https://www.ncbi.nlm.nih.gov/pubmed/30416295
http://dx.doi.org/10.4103/ipj.ipj_27_18
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