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Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

The formation of intraneuronal fibrillar inclusions of tau protein is associated with several neurodegenerative diseases referred to as tauopathies including Alzheimer's disease (AD). A common feature of these pathologies is hyperphosphorylation of tau, the main component of fibrillar assemblie...

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Detalles Bibliográficos
Autores principales: Bourré, Gwendoline, Cantrelle, François-Xavier, Kamah, Amina, Chambraud, Béatrice, Landrieu, Isabelle, Smet-Nocca, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198643/
https://www.ncbi.nlm.nih.gov/pubmed/30386294
http://dx.doi.org/10.3389/fendo.2018.00595