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Transforming Growth Factor β1 (TGF-β1) Appears to Promote Coronary Artery Disease by Upregulating Sphingosine Kinase 1 (SPHK1) and Further Upregulating Its Downstream TIMP-1

BACKGROUND: Transforming growth factor (TGF)-β1 is involved in the pathogenesis of coronary artery disease (CAD), but the mechanism of its action remains unclear. Our study aimed to investigate the role of TGF-β1 in CAD and to explore the possible mechanisms. MATERIAL/METHODS: A total of 60 CAD pati...

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Detalles Bibliográficos
Autores principales:	Wang, Shoudong, Zhang, Qing, Wang, Yingcui, You, Beian, Meng, Qingfeng, Zhang, Sen, Li, Xuanlong, Ge, Zhiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198708/ https://www.ncbi.nlm.nih.gov/pubmed/30317247 http://dx.doi.org/10.12659/MSM.910707

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