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High prevalence and long duration of nervous system and psychiatric adverse drug reactions in Ugandan patients taking efavirenz 600 mg daily

BACKGROUND: Efavirenz-related nervous system or psychiatric adverse drug reactions (ADRs) are conventionally reported to resolve soon after initiation, with incidence of dizziness at 8.5% in large clinical trials. Patients of black ethnicity are genetically at greater risk of elevated efavirenz expo...

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Detalles Bibliográficos
Autores principales: Seden, Kay, Kiiza, Daniel, Laker, Eva, Arinaitwe, Walter J, Waitt, Catriona, Lamorde, Mohammed, Khoo, Saye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198741/
https://www.ncbi.nlm.nih.gov/pubmed/30085168
http://dx.doi.org/10.1093/jac/dky298