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A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation

AIMS: Endothelial hyperpermeability exacerbates multiple organ damage during inflammation or infection. The endothelial glycocalyx, a protective matrix covering the luminal surface of endothelial cells (ECs), undergoes enzymatic shedding during inflammation, contributing to barrier hyperpermeability...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyuan, Meegan, Jamie E, Jannaway, Melanie, Coleman, Danielle C, Yuan, Sarah Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198742/
https://www.ncbi.nlm.nih.gov/pubmed/29939250
http://dx.doi.org/10.1093/cvr/cvy167