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A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation
AIMS: Endothelial hyperpermeability exacerbates multiple organ damage during inflammation or infection. The endothelial glycocalyx, a protective matrix covering the luminal surface of endothelial cells (ECs), undergoes enzymatic shedding during inflammation, contributing to barrier hyperpermeability...
Autores principales: | Yang, Xiaoyuan, Meegan, Jamie E, Jannaway, Melanie, Coleman, Danielle C, Yuan, Sarah Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198742/ https://www.ncbi.nlm.nih.gov/pubmed/29939250 http://dx.doi.org/10.1093/cvr/cvy167 |
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