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Enantiospecific pharmacokinetics and drug–drug interactions of primaquine and blood-stage antimalarial drugs

OBJECTIVES: Characterization of the pharmacokinetic properties of the enantiomers of primaquine and carboxyprimaquine following administration of racemic primaquine given alone and in combination with commonly used antimalarial drugs. METHODS: Enantiomeric pharmacokinetics were evaluated in 49 healt...

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Detalles Bibliográficos
Autores principales:	Chairat, Kalayanee, Jittamala, Podjanee, Hanboonkunupakarn, Borimas, Pukrittayakamee, Sasithon, Hanpithakpong, Warunee, Blessborn, Daniel, White, Nicholas J, Day, Nicholas P J, Tarning, Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198747/ https://www.ncbi.nlm.nih.gov/pubmed/30085149 http://dx.doi.org/10.1093/jac/dky297

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