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Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites

BACKGROUND: Endogenous nitric oxide (NO) may contribute to ischemic and anesthetic preconditioning while exogenous NO protects against ischemia-reperfusion (I/R) injury in the heart and other organs. Why those beneficial effects observed in animal models do not always translate into clinical effecti...

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Detalles Bibliográficos
Autores principales: Nagasaka, Yasuko, Fernandez, Bernadette O., Steinbicker, Andrea U., Spagnolli, Ester, Malhotra, Rajeev, Bloch, Donald B., Bloch, Kenneth D., Zapol, Warren M., Feelisch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198794/
https://www.ncbi.nlm.nih.gov/pubmed/30114529
http://dx.doi.org/10.1016/j.niox.2018.08.006