Effect of CCR2 inhibitor-loaded lipid micelles on inflammatory cell migration and cardiac function after myocardial infarction

BACKGROUND: After myocardial infarction (MI), inflammatory cells infiltrate the infarcted heart in response to secreted stimuli. Monocytes are recruited to the infarct via CCR2 chemokine receptors along a CCL2 concentration gradient. While infiltration of injured tissue with monocytes is an importan...

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Detalles Bibliográficos
Autores principales: Wang, Jinli, Seo, Min Jeong, Deci, Michael B, Weil, Brian R, Canty, John M, Nguyen, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198873/
https://www.ncbi.nlm.nih.gov/pubmed/30410330

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