Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation

Alport syndrome is an inherited disorder of basement membrane collagen IV that frequently results in end-stage renal disease. Patients with Alport syndrome who undergo renal transplantation have generally excellent outcomes. Posttransplant antiglomerular basement membrane nephritis is a rare complic...

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Detalles Bibliográficos
Autor principal: Kashtan, Clifford E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198874/
https://www.ncbi.nlm.nih.gov/pubmed/30410383
http://dx.doi.org/10.2147/IJNRD.S150539
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author Kashtan, Clifford E
author_facet Kashtan, Clifford E
author_sort Kashtan, Clifford E
collection PubMed
description Alport syndrome is an inherited disorder of basement membrane collagen IV that frequently results in end-stage renal disease. Patients with Alport syndrome who undergo renal transplantation have generally excellent outcomes. Posttransplant antiglomerular basement membrane nephritis is a rare complication of renal transplantation for Alport syndrome. Because Alport syndrome is a genetic disorder, potential related donors must be carefully evaluated in order to minimize harm.
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spelling pubmed-61988742018-11-08 Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation Kashtan, Clifford E Int J Nephrol Renovasc Dis Review Alport syndrome is an inherited disorder of basement membrane collagen IV that frequently results in end-stage renal disease. Patients with Alport syndrome who undergo renal transplantation have generally excellent outcomes. Posttransplant antiglomerular basement membrane nephritis is a rare complication of renal transplantation for Alport syndrome. Because Alport syndrome is a genetic disorder, potential related donors must be carefully evaluated in order to minimize harm. Dove Medical Press 2018-10-16 /pmc/articles/PMC6198874/ /pubmed/30410383 http://dx.doi.org/10.2147/IJNRD.S150539 Text en © 2018 Kashtan. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Kashtan, Clifford E
Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation
title Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation
title_full Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation
title_fullStr Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation
title_full_unstemmed Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation
title_short Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation
title_sort renal transplantation in patients with alport syndrome: patient selection, outcomes, and donor evaluation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198874/
https://www.ncbi.nlm.nih.gov/pubmed/30410383
http://dx.doi.org/10.2147/IJNRD.S150539
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