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Clinical use of FLT3 inhibitors in acute myeloid leukemia

Acute myeloid leukemia (AML) is a highly heterogeneous disease. Mutation with internal tandem duplication of fms-like tyrosine kinase-3 (FLT3-ITD) is one of the two most common driver mutations and the presence of FLT3-ITD delivers poor prognosis. A number of ongoing clinical efforts are focused on...

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Detalles Bibliográficos
Autores principales: Sutamtewagul, Grerk, Vigil, Carlos E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198878/
https://www.ncbi.nlm.nih.gov/pubmed/30410361
http://dx.doi.org/10.2147/OTT.S171640

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