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The dimeric structure of wild-type human glycosyltransferase B4GalT1
Most glycosyltransferases, including B4GalT1 (EC 2.4.1.38), are known to assemble into enzyme homomers and functionally relevant heteromers in vivo. However, it remains unclear why and how these enzymes interact at the molecular/atomic level. Here, we solved the crystal structure of the wild-type hu...
Autores principales: | Harrus, Deborah, Khoder-Agha, Fawzi, Peltoniemi, Miika, Hassinen, Antti, Ruddock, Lloyd, Kellokumpu, Sakari, Glumoff, Tuomo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198961/ https://www.ncbi.nlm.nih.gov/pubmed/30352055 http://dx.doi.org/10.1371/journal.pone.0205571 |
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