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Bioprocess development of antibody-drug conjugate production for cancer treatment

Antibody-drug conjugate (ADC) is a class of targeted cancer therapies that combine the advantages of monoclonal antibody (mAb)’s specific targeting and chemotherapy’s potent cytotoxicity. The therapeutic effect of ADC is significantly affected by its bioproduction process. This study aims to develop...

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Detalles Bibliográficos
Autores principales: Ou, Jianfa, Si, Yingnan, Goh, KahYong, Yasui, Norio, Guo, Yichen, Song, Jiajia, Wang, Lizhong, Jaskula-Sztul, Renata, Fan, Jinda, Zhou, Lufang, Liu, Runhua, Liu, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198984/
https://www.ncbi.nlm.nih.gov/pubmed/30352095
http://dx.doi.org/10.1371/journal.pone.0206246