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Synchronous Triple Malignancies in an Indian Albino: A Case Report

Oculocutaneous albinism (OCA) is a heterogenous disorder of skin pigmentation characterized by hypopigmentation of the skin, hair, and eyes. The absence of melanin predisposes these individuals to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in...

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Autores principales: Darlington, Danny, Puthanmadhom Narayanan, Susrutha, Anitha, Fatima Shirly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199145/
https://www.ncbi.nlm.nih.gov/pubmed/30364818
http://dx.doi.org/10.7759/cureus.3190
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author Darlington, Danny
Puthanmadhom Narayanan, Susrutha
Anitha, Fatima Shirly
author_facet Darlington, Danny
Puthanmadhom Narayanan, Susrutha
Anitha, Fatima Shirly
author_sort Darlington, Danny
collection PubMed
description Oculocutaneous albinism (OCA) is a heterogenous disorder of skin pigmentation characterized by hypopigmentation of the skin, hair, and eyes. The absence of melanin predisposes these individuals to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in OCA have been rarely reported. Malignant melanoma (MM) of the skin is also very rarely reported. Synchronous BCC, SCC, and MM are exceedingly rare. We report one such case managed successfully with surgical treatment. All the three malignancies were localized cancers and hence the outcome was good. The importance of regular follow up and periodic self-examination in such predisposed individuals are highlighted.
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spelling pubmed-61991452018-10-24 Synchronous Triple Malignancies in an Indian Albino: A Case Report Darlington, Danny Puthanmadhom Narayanan, Susrutha Anitha, Fatima Shirly Cureus Dermatology Oculocutaneous albinism (OCA) is a heterogenous disorder of skin pigmentation characterized by hypopigmentation of the skin, hair, and eyes. The absence of melanin predisposes these individuals to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in OCA have been rarely reported. Malignant melanoma (MM) of the skin is also very rarely reported. Synchronous BCC, SCC, and MM are exceedingly rare. We report one such case managed successfully with surgical treatment. All the three malignancies were localized cancers and hence the outcome was good. The importance of regular follow up and periodic self-examination in such predisposed individuals are highlighted. Cureus 2018-08-23 /pmc/articles/PMC6199145/ /pubmed/30364818 http://dx.doi.org/10.7759/cureus.3190 Text en Copyright © 2018, Darlington et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Darlington, Danny
Puthanmadhom Narayanan, Susrutha
Anitha, Fatima Shirly
Synchronous Triple Malignancies in an Indian Albino: A Case Report
title Synchronous Triple Malignancies in an Indian Albino: A Case Report
title_full Synchronous Triple Malignancies in an Indian Albino: A Case Report
title_fullStr Synchronous Triple Malignancies in an Indian Albino: A Case Report
title_full_unstemmed Synchronous Triple Malignancies in an Indian Albino: A Case Report
title_short Synchronous Triple Malignancies in an Indian Albino: A Case Report
title_sort synchronous triple malignancies in an indian albino: a case report
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199145/
https://www.ncbi.nlm.nih.gov/pubmed/30364818
http://dx.doi.org/10.7759/cureus.3190
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