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Synchronous Triple Malignancies in an Indian Albino: A Case Report
Oculocutaneous albinism (OCA) is a heterogenous disorder of skin pigmentation characterized by hypopigmentation of the skin, hair, and eyes. The absence of melanin predisposes these individuals to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199145/ https://www.ncbi.nlm.nih.gov/pubmed/30364818 http://dx.doi.org/10.7759/cureus.3190 |
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author | Darlington, Danny Puthanmadhom Narayanan, Susrutha Anitha, Fatima Shirly |
author_facet | Darlington, Danny Puthanmadhom Narayanan, Susrutha Anitha, Fatima Shirly |
author_sort | Darlington, Danny |
collection | PubMed |
description | Oculocutaneous albinism (OCA) is a heterogenous disorder of skin pigmentation characterized by hypopigmentation of the skin, hair, and eyes. The absence of melanin predisposes these individuals to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in OCA have been rarely reported. Malignant melanoma (MM) of the skin is also very rarely reported. Synchronous BCC, SCC, and MM are exceedingly rare. We report one such case managed successfully with surgical treatment. All the three malignancies were localized cancers and hence the outcome was good. The importance of regular follow up and periodic self-examination in such predisposed individuals are highlighted. |
format | Online Article Text |
id | pubmed-6199145 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-61991452018-10-24 Synchronous Triple Malignancies in an Indian Albino: A Case Report Darlington, Danny Puthanmadhom Narayanan, Susrutha Anitha, Fatima Shirly Cureus Dermatology Oculocutaneous albinism (OCA) is a heterogenous disorder of skin pigmentation characterized by hypopigmentation of the skin, hair, and eyes. The absence of melanin predisposes these individuals to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in OCA have been rarely reported. Malignant melanoma (MM) of the skin is also very rarely reported. Synchronous BCC, SCC, and MM are exceedingly rare. We report one such case managed successfully with surgical treatment. All the three malignancies were localized cancers and hence the outcome was good. The importance of regular follow up and periodic self-examination in such predisposed individuals are highlighted. Cureus 2018-08-23 /pmc/articles/PMC6199145/ /pubmed/30364818 http://dx.doi.org/10.7759/cureus.3190 Text en Copyright © 2018, Darlington et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Darlington, Danny Puthanmadhom Narayanan, Susrutha Anitha, Fatima Shirly Synchronous Triple Malignancies in an Indian Albino: A Case Report |
title | Synchronous Triple Malignancies in an Indian Albino: A Case Report |
title_full | Synchronous Triple Malignancies in an Indian Albino: A Case Report |
title_fullStr | Synchronous Triple Malignancies in an Indian Albino: A Case Report |
title_full_unstemmed | Synchronous Triple Malignancies in an Indian Albino: A Case Report |
title_short | Synchronous Triple Malignancies in an Indian Albino: A Case Report |
title_sort | synchronous triple malignancies in an indian albino: a case report |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199145/ https://www.ncbi.nlm.nih.gov/pubmed/30364818 http://dx.doi.org/10.7759/cureus.3190 |
work_keys_str_mv | AT darlingtondanny synchronoustriplemalignanciesinanindianalbinoacasereport AT puthanmadhomnarayanansusrutha synchronoustriplemalignanciesinanindianalbinoacasereport AT anithafatimashirly synchronoustriplemalignanciesinanindianalbinoacasereport |