Genome-wide characterization of the seasonal H3N2 virus in Shanghai reveals natural temperature-sensitive strains conferred by the I668V mutation in the PA subunit

Seasonal H3N2 influenza viruses are recognized as major epidemic viruses, exhibiting complex seasonal patterns in regions with temperate climates. To investigate the influence of viral evolution and mutations on the seasonality of influenza, we performed a genome-wide analysis of samples collected f...

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Detalles Bibliográficos
Autores principales: Wei, Dong, Yu, De-Ming, Wang, Ming-jie, Zhang, Dong-hua, Cheng, Qi-jian, Qu, Jie-Ming, Zhang, Xin-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199244/
https://www.ncbi.nlm.nih.gov/pubmed/30353004
http://dx.doi.org/10.1038/s41426-018-0172-4

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