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Molecular mechanism of substrate selectivity of the arginine-agmatine Antiporter AdiC

The arginine-agmatine antiporter (AdiC) is a component of an acid resistance system developed by enteric bacteria to resist gastric acidity. In order to avoid neutral proton antiport, the monovalent form of arginine, about as abundant as its divalent form under acidic conditions, should be selective...

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Detalles Bibliográficos
Autores principales: Krammer, Eva-Maria, Gibbons, Andrew, Roos, Goedele, Prévost, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199258/
https://www.ncbi.nlm.nih.gov/pubmed/30353119
http://dx.doi.org/10.1038/s41598-018-33963-1