Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL

The ATP-binding cassette transporter TAPL translocates polypeptides from the cytosol into the lysosomal lumen. TAPL can be divided into two functional units: coreTAPL, active in ATP-dependent peptide translocation, and the N-terminal membrane spanning domain, TMD0, responsible for cellular localizat...

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Detalles Bibliográficos
Autores principales: Bock, Christoph, Löhr, Frank, Tumulka, Franz, Reichel, Katrin, Würz, Julia, Hummer, Gerhard, Schäfer, Lars, Tampé, Robert, Joseph, Benesh, Bernhard, Frank, Dötsch, Volker, Abele, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199259/
https://www.ncbi.nlm.nih.gov/pubmed/30353140
http://dx.doi.org/10.1038/s41598-018-33841-w

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