Oligodendrocyte differentiation of induced pluripotent stem cells derived from subjects with schizophrenias implicate abnormalities in development

Abnormalities of brain connectivity and signal transduction are consistently observed in individuals with schizophrenias (SZ). Underlying these anomalies, convergent in vivo, post mortem, and genomic evidence suggest abnormal oligodendrocyte (OL) development and function and lower myelination in SZ....

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Detalles Bibliográficos
Autores principales: McPhie, Donna L., Nehme, Ralda, Ravichandran, Caitlin, Babb, Suzann M., Ghosh, Sulagna Dia, Staskus, Alexandra, Kalinowski, Amy, Kaur, Rupinderjit, Douvaras, Panagiotis, Du, Fei, Ongur, Dost, Fossati, Valentina, Eggan, Kevin, Cohen, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199264/
https://www.ncbi.nlm.nih.gov/pubmed/30352993
http://dx.doi.org/10.1038/s41398-018-0284-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199264/
https://www.ncbi.nlm.nih.gov/pubmed/30352993
http://dx.doi.org/10.1038/s41398-018-0284-6

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