Cargando…
Stable Frequencies of HLA-C(*)03:04/Peptide-Binding KIR2DL2/3(+) Natural Killer Cells Following Vaccination
Inhibitory KIRs play a central role in regulating NK cell activity. KIR2DL2/3 bind to HLA-C molecules, but the modulation of these interactions by viral infections and presentation of viral epitopes is not well-understood. We investigated whether the frequencies of KIR2DL2/3(+) NK cells recognizing...
Autores principales: | Ziegler, Maja Christiane, Grañana, Ferran Borràs, Garcia-Beltran, Wilfredo F., Schulze zur Wiesch, Julian, Hoffmann, Christian, Rechtien, Anne, Lunemann, Sebastian, Altfeld, Marcus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199360/ https://www.ncbi.nlm.nih.gov/pubmed/30386333 http://dx.doi.org/10.3389/fimmu.2018.02361 |
Ejemplares similares
-
Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01
por: Salzberger, Wilhelm, et al.
Publicado: (2015) -
HIV-1 induced changes in HLA-C∗03 : 04-presented peptide repertoires lead to reduced engagement of inhibitory natural killer cell receptors
por: Ziegler, Maja C., et al.
Publicado: (2020) -
Peptide-specific engagement of the activating NK cell receptor KIR2DS1
por: Chapel, Anaïs, et al.
Publicado: (2017) -
Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa
por: Hölzemer, Angelique, et al.
Publicado: (2015) -
HIV-1 p24 derived epitopes modulate KIR2DL2-binding to HLA-Cw03
por: van Teijlingen, NH, et al.
Publicado: (2012)