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Heterologous Immunization With Defined RNA and Subunit Vaccines Enhances T Cell Responses That Protect Against Leishmania donovani
The rapid generation of strong T cell responses is highly desirable and viral vectors can have potent CD8(+) T cell-inducing activity. Immunity to leishmaniasis requires selective T cell responses, with immunization schemes that raise either CD4 or CD8 T cell responses being protective in small anim...
Autores principales: | Duthie, Malcolm S., Van Hoeven, Neal, MacMillen, Zachary, Picone, Alessandro, Mohamath, Raodoh, Erasmus, Jesse, Hsu, Fan-Chi, Stinchcomb, Dan T., Reed, Steven G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199377/ https://www.ncbi.nlm.nih.gov/pubmed/30386348 http://dx.doi.org/10.3389/fimmu.2018.02420 |
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