Peripheral Dopamine Controlled by Gut Microbes Inhibits Invariant Natural Killer T Cell-Mediated Hepatitis

Neurotransmitters have been shown to regulate immune responses, and thereby are critically related to autoimmune diseases. Here we showed that depletion of dopaminergic neurons significantly promoted activation of hepatic iNKT cells and augmented concanavalin A (Con A)-induced liver injury. The supp...

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Detalles Bibliográficos
Autores principales: Xue, Rufeng, Zhang, Huimin, Pan, Jun, Du, Zhiwei, Zhou, Wenjie, Zhang, Zhi, Tian, Zhigang, Zhou, Rongbin, Bai, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199378/
https://www.ncbi.nlm.nih.gov/pubmed/30386344
http://dx.doi.org/10.3389/fimmu.2018.02398

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