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Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains

BACKGROUND: In animals with XY sex chromosomes, X-linked genes from a single X chromosome in males are imbalanced relative to autosomal genes. To minimize the impact of genic imbalance in male Drosophila, there is a dosage compensation complex (MSL) that equilibrates X-linked gene expression with th...

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Detalles Bibliográficos
Autores principales: Lee, Hangnoh, Oliver, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199721/
https://www.ncbi.nlm.nih.gov/pubmed/30355339
http://dx.doi.org/10.1186/s13072-018-0232-y