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PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses
Mitochondria regulate not only cell functions through energy generation but also aging-associated cell phenotypes. Impaired mitochondrial structural and functional integrity accompanied by excessive mitochondrial reactive oxygen species (mtROS) production is associated with enhanced programmed cell...
Autores principales: | Tsubouchi, Kazuya, Araya, Jun, Kuwano, Kazuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199723/ https://www.ncbi.nlm.nih.gov/pubmed/30386443 http://dx.doi.org/10.1186/s41232-018-0077-6 |
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