Evaluation of aflibercept and ziv-aflibercept binding affinity to vascular endothelial growth factor, stability and sterility after compounding

PURPOSE: To investigate the binding affinity, stability, and sterility of aflibercept and ziv-aflibercept to vascular endothelial growth factor (Holash et al. in Proc Natl Acad Sci USA 99(17):11393–11398, 2002. 10.1073/pnas.172398299) after compounding and storage for up to 28 days at 4 °C and − 8 °...

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Detalles Bibliográficos
Autores principales: de Lima Farah, Julia, Sano, Ronaldo, Maugéri, Ieda Maria Longo, Teixeira, Daniela, Ishimura, Mayari Eika, Martins, Gabriela, Mimica, Lycia M. J., da Silva, Cely Barreto, Meyer, Carsten H., de Oliveira Dias, João Rafael, de Andrade, Gabriel Costa, Farah, Michel Eid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199727/
https://www.ncbi.nlm.nih.gov/pubmed/30386633
http://dx.doi.org/10.1186/s40942-018-0143-x

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