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The role of integration and clonal expansion in HIV infection: live long and prosper

Integration of viral DNA into the host genome is a central event in the replication cycle and the pathogenesis of retroviruses, including HIV. Although most cells infected with HIV are rapidly eliminated in vivo, HIV also infects long-lived cells that persist during combination antiretroviral therap...

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Detalles Bibliográficos
Autores principales: Anderson, Elizabeth M., Maldarelli, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199739/
https://www.ncbi.nlm.nih.gov/pubmed/30352600
http://dx.doi.org/10.1186/s12977-018-0448-8