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Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome

BACKGROUND: Efficient and sustained hematopoietic recovery after hematopoietic stem cell or bone marrow transplantation is supported by paracrine signaling from specific subpopulations of mesenchymal stromal cells (MSCs). Here, we considered whether in vitro mechanopriming of human MSCs could be adm...

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Detalles Bibliográficos
Autores principales: Liu, Frances D., Tam, Kimberley, Pishesha, Novalia, Poon, Zhiyong, Van Vliet, Krystyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199758/
https://www.ncbi.nlm.nih.gov/pubmed/30352620
http://dx.doi.org/10.1186/s13287-018-0982-2