Analysis of large deletion mutations induced by abasic site analog in human cells

BACKGROUND: Abasic sites are formed spontaneously and by nucleobase chemical modifications and base excision repair. A chemically stable abasic site analog was site-specifically introduced into replicable plasmid DNAs, which were transfected into human U2OS cells. The amplified DNAs were recovered f...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Tetsuya, Katayama, Yuri, Komatsu, Yasuo, Kamiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199760/
https://www.ncbi.nlm.nih.gov/pubmed/30386442
http://dx.doi.org/10.1186/s41021-018-0110-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199760/
https://www.ncbi.nlm.nih.gov/pubmed/30386442
http://dx.doi.org/10.1186/s41021-018-0110-7

Ejemplares similares